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North East »» Tripura gets new Chief Secretary•••Manipur towns resemble garrisoned towns•••State »» Ration cards to be distributed under Food Security Act•••Workshop for children’s cultural development concludes•••BNC asks BSS to reconsider decision to part ways•••National »» ’Don’t treat children as adults’•••’Old fears’ of cultural polarisation rising in Goa •••Maharashtra landslide toll 31, Rajnath assures all possible help•••International »» ’No ceasefire without destruction of tunnels’•••International experts reach MH17 crash site•••’Snowden awaits Russia’s nod on extended asylum’•••    
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Scientists discover better drugs for sleep problems
 

Washington, April 9: The discovery of cellular switches in the bio-clock that tells the body when to sleep and metabolise food may lead to new drugs to treat sleep problems and metabolic disorders, including diabetes. Scientists at the Salk Institute for Biological Studies, led by Ronald M. Evans, professor in its Gene Expression Lab, showed that two cellular switches found on the nucleus of mouse cells, known as REV-ERBa and REV-ERBß, are essential for maintaining normal sleeping and eating cycles and for metabolism of nutrients from food. The findings describe a powerful link between circadian rhythms and metabolism and suggest a new avenue for treating disorders of both systems, including jet lag, sleep disorders, obesity and diabetes, the journal Nature reported. “This fundamentally changes our knowledge about the workings of the circadian clock and how it orchestrates our sleep-wake cycles, when we eat and even the times our bodies metabolize nutrients,” said Evans, according to a university statement. “Nuclear (pertaining to nucleus) receptors can be targeted with drugs, which suggests we might be able to target REV-ERBa and ß to treat disorders of sleep and metabolism,” added Evans. Nurses, emergency personnel and others who work shifts that alter the normal 24-hour cycle of waking and sleeping are at much higher risk for a number of diseases, including metabolic disorders such as diabetes. In mammals, the circadian timing system is orchestrated by a central clock in the brain and subsidiary clocks in most other organs. The master clock in the brain is set by light and determines the overall diurnal or nocturnal preference of an animal, including sleep-wake cycles and feeding behaviour. (IANS)

       
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Guwahati
34.5oC
25.0oC
Dibrugarh
33.4oC
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Shillong
25.2oC
18.3oC
Imphal
31.8oC
23.3oC
Kohima
26.2oC
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Itanagar
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Rain/thundershowers would occur at a few places over Arunachal Pradesh, Assam, Meghalaya, Nagaland, Manipur, Mizoram & Tripura.
 Arunachal News
Assembly refers Bill to select Committee
ANSU calls for urgent steps to tackle JE
’Shifting of NHPC office put to halt’
’Work on Greenfield Airport to start soon’
 Meghalaya News
Mukul sends letter to PM on coal mining
HNLC abducting people
24 ANVC (B) members arrested
First Circular Eco Hatchery inaugurated
 Northeast News
Tripura gets new Chief Secretary
Manipur towns resemble garrisoned towns
 Cachar News
Congress gearing up for Silchar by poll
Sangram Committee seeks clarification of Railway Minister’s statement
Manipuri Diaspora Assam condemns brutal killing of Hirendra Singha
Five labourers buried alive under debris
 National News
’Don’t treat children as adults’
’Old fears’ of cultural polarisation rising in Goa
Maharashtra landslide toll 31, Rajnath assures all possible help
’Reaching out to the innovators and people’
 International News
’No ceasefire without destruction of tunnels’
International experts reach MH17 crash site
’Snowden awaits Russia’s nod on extended asylum’
Moroccan king stresses moderation in Islam
 State-1
Ration cards to be distributed under Food Security Act
Workshop for children’s cultural development concludes
BNC asks BSS to reconsider decision to part ways
Red Horn Division troops apprehended one terrorist of NSLA (AT)
 State-2
TWDOCAC facing obstruction in implementation of welfare schemes
Appeal to take steps against erosion
SULFA man arrested on extortion charges
 Local Sports
’A’ Division matches abandoned
Who is responsible ?
 Sports
England roar back as India crumble to Moeen
’Ishant to miss fourth Test’
Cook all praise for Moeen
Yogeshwar, Babita win wrestling golds for India
 Editorial
Skill Development
Russia seeks to promote its culture in India
’Preparing a blueprint to Indianise education’
Letters to the Editor
 Op-Ed (Sunday)
Geographical Perspective of Artificial Flood in Guwahati
Subansiri project: Some facts
A TALE OF GRAND PARENTS
 
Assam
 
Assam is a northeastern state of India with its capital at Dispur located in the city of Guwahati.
 
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Nagaland
 
Nagaland is a northeastern state of India with its capital at Kohima. located in the Guwahati city.
 
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Mizoram
 
Mizoram is a northeastern state of India with its capital at Aizwal. located in the Guwahati city.
 
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Meghalaya
 
Meghalaya is a northeastern state of India with its capital at Shillong. located in the Guwahati.
 
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Manipur
 
Manipur is a northeastern state of India with its capital at Imphal.
 
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Tripura
 
Tripura is a northeastern state of India with its capital at Agartala.
 
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Arunachal Pradesh
 
Arunachal Pradesh is a northeastern state of India with its capital at Itanagar.
 
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Sikkim
 
Sikkim is a northeastern state of India with its capital at Gangtok.
 
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