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North East »» Bangladeshis among five arrested in Mizoram•••World Bank to give $107 mn for road project in Mizoram•••Manipur bids farewell to its Governor•••State »» JE forecast system for Dibrugarh•••Worry over lack of teaching staff at Namrup KV•••Chairman Mohan Tisso inaugurates PMJDY programme•••National »» Modi tones up governance, lays out policy roadmap•••’I used the word Hindi not Hindu’•••’Start talks with Pakistan’•••International »» NATO accuses Russia of direct involvement in Ukraine crisis •••Putin urges Ukraine militants to open humanitarian corridor•••Obama blames Russia for east Ukraine violence•••    
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Scientists discover better drugs for sleep problems
 

Washington, April 9: The discovery of cellular switches in the bio-clock that tells the body when to sleep and metabolise food may lead to new drugs to treat sleep problems and metabolic disorders, including diabetes. Scientists at the Salk Institute for Biological Studies, led by Ronald M. Evans, professor in its Gene Expression Lab, showed that two cellular switches found on the nucleus of mouse cells, known as REV-ERBa and REV-ERBß, are essential for maintaining normal sleeping and eating cycles and for metabolism of nutrients from food. The findings describe a powerful link between circadian rhythms and metabolism and suggest a new avenue for treating disorders of both systems, including jet lag, sleep disorders, obesity and diabetes, the journal Nature reported. “This fundamentally changes our knowledge about the workings of the circadian clock and how it orchestrates our sleep-wake cycles, when we eat and even the times our bodies metabolize nutrients,” said Evans, according to a university statement. “Nuclear (pertaining to nucleus) receptors can be targeted with drugs, which suggests we might be able to target REV-ERBa and ß to treat disorders of sleep and metabolism,” added Evans. Nurses, emergency personnel and others who work shifts that alter the normal 24-hour cycle of waking and sleeping are at much higher risk for a number of diseases, including metabolic disorders such as diabetes. In mammals, the circadian timing system is orchestrated by a central clock in the brain and subsidiary clocks in most other organs. The master clock in the brain is set by light and determines the overall diurnal or nocturnal preference of an animal, including sleep-wake cycles and feeding behaviour. (IANS)

       
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Guwahati
36.0oC
24.2oC
Dibrugarh
34.8oC
24.9oC
Shillong
26.9oC
17.5oC
Imphal
32.2oC
22.8oC
Kohima
27.7oC
16.7oC
Itanagar
NAoC
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Rain/thundershowers would occur at many places over Arunachal Pradesh, Assam, Meghalaya, Nagaland, Manipur, Mizoram & Tripura.
 Arunachal News
Flood creates havoc in Bordumsa–Diyum
State inks MoU with NEDFi
’Centre planning two road projects for Arunachal’
Government agrees to ANSU’s demands
 Meghalaya News
Government ready for talks with HNLC
Five ANCA cadres arrested
’ANVC (B) out to wipe out renegades’
Four die in road mishap
 Northeast News
Bangladeshis among five arrested in Mizoram
World Bank to give $107 mn for road project in Mizoram
Manipur bids farewell to its Governor
 Cachar News
’Take action against illicit liquor business & betting dens’
Exhibition on Science & Social Science in Don Bosco earns applaud
BSF nabs individuals with arms and ammunition
Residents of Salchapra & Srikona areas demand adequate bus services
 National News
Modi tones up governance, lays out policy roadmap
’I used the word Hindi not Hindu’
’Start talks with Pakistan’
’Mamata must stop Modi from changing land acquisition act’
 International News
NATO accuses Russia of direct involvement in Ukraine crisis
Putin urges Ukraine militants to open humanitarian corridor
Obama blames Russia for east Ukraine violence
’Haven’t sought army’s mediation in political crisis’
 State-1
JE forecast system for Dibrugarh
Worry over lack of teaching staff at Namrup KV
Chairman Mohan Tisso inaugurates PMJDY programme
Federal Bank Employees’ Union calls for All India Strike
 State-2
Robbers kill senior lawyer in Mangaldai
Protests continue in BTAD over Priya Basumatary killings
Arms, ammunition recovered from ULFA cadre
Stage set for Jamunamukh polls
 Local Sports
Next State Games to be held in Silchar
Green Valley, ASEBSC share points
AP Blues finish with a win
Trial Camp
 Sports
Paes–Cara, Bopanna–Katarina advance in mixed doubles
Campbell–Brown wins photo finish
Panel probing IPL spot–fixing, betting submits report
Sports minister pays tribute to Dhyan Chand on birth anniversary
 Editorial
SC on Charged Ministers
Islam: A Revolution in the Offing?
Trade, culture redeem dented India–Pakistan ties
Letters to the Editor
 Op-Ed (Sunday)
The difficult task of finding friends and foes in West Asia
Congress vows comeback in Bengal
Social Role of Gita
 
Assam
 
Assam is a northeastern state of India with its capital at Dispur located in the city of Guwahati.
 
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Nagaland
 
Nagaland is a northeastern state of India with its capital at Kohima. located in the Guwahati city.
 
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Mizoram
 
Mizoram is a northeastern state of India with its capital at Aizwal. located in the Guwahati city.
 
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Meghalaya
 
Meghalaya is a northeastern state of India with its capital at Shillong. located in the Guwahati.
 
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Manipur
 
Manipur is a northeastern state of India with its capital at Imphal.
 
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Tripura
 
Tripura is a northeastern state of India with its capital at Agartala.
 
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Arunachal Pradesh
 
Arunachal Pradesh is a northeastern state of India with its capital at Itanagar.
 
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Sikkim
 
Sikkim is a northeastern state of India with its capital at Gangtok.
 
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