Due to the absence of routine screening, more than 80% of those who are genetically predisposed to have Cancer are unaware about their risk for cancers of the breast, ovarian, prostate and pancreas, a study of over 50,000 people has shown. Most people only discover that they carry the disease-associated variants in the BRCA1 or BRCA2 genes when that person or family members receive a cancer diagnosis.
Obesity coupled with vitamin D deficiency in postmenopausal women may pose a significant risk of breast cancer awareness as it the most common and leading cause of death in women as per the study. Breast cancer is the most common among all cancers that are found in women worldwide. Vitamin D helps us to build bone strength and immunity. Women, especially ones in their middle age should intake vitamin D in huge amount. Studies have found that higher levels of vitamin D may reduce the disease mortality by 50 percent in women with lower body mass index (BMI).
According to a study, vitamin D reduces the risk of the disease by inhibiting cell proliferation. The researching team found breast cancer in more than 600 Brazilian women. The higher levels of vitamin D in the body are associated with lowered chances of the disease risk, as vitamin D plays a significant role in controlling breast cancer cells or stopping them from growing. Vitamin D comes from direct sunlight exposure, vitamin D3 supplements, or Foods that are enriched with vitamin D.
Some of the experts say that it usually takes a tragedy for people to get tested, their reliance on a documented personal or family history as a trigger to offer testing is not working. Hopefully, one day there can be a change that with effective DNA-based screening for everyone.
The mean age of subjects in the study was 60. Two hundred and sixty-seven of those screened possessed a BRCA risk variant, yet only 18% of them were aware they possessed this risk factor for cancer prior to being informed by the study.
Among the group of living BRCA-positive patients, 16.8% of them had BRCA-associated cancer. In the small group of BRCA-positive patients who had died before the study’s conclusion, 47.8% of them had BRCA-associated cancer.
“Once risk is identified, we can apply proven tools for early diagnosis and prevention, and we believe that the 31% difference in disease incidence in these two groups is a window into an opportunity to decrease the disease and cancer deaths through genomic screening approaches,” Expert say.