How to reverse signs of ageing

New York, July 21: Scientists, including one of Indian origin, have found the way to reverse the action of wrinkled skin and hair loss which are considered as the hallmarks of ageing, in a mouse model. The findings showed that, when a mutation leading to mitochondrial dysfunction is induced, the mouse develops wrinkled skin and extensive, visible hair loss in a matter of weeks. However, when the mitochondrial function is restored by turning off the gene responsible for its dysfunction, the mouse returns to smooth skin and thick fur, indistinguishable from a healthy mouse of the same age. According to the study authors, the decline in mitochondrial function among humans is seen during ageing, and can drive age-related diseases. (IANS)