Biopharma Hub to come up at Hyderabad's Genome Valley

HYDERABAD: To give impetus to biopharmaceutical research and manufacturing, the Telangana government on Sunday announced that it is developing Biopharma Hub (B-hub), which will be first of its kind growth phase centre and biopharma scale-up manufacturing facility in India.

Industry and Information Technology Minister K. T. Rama Rao tweeted that B-Hub will be operational in 15 months and will help consolidate Telangana's leadership position in biopharma.

"With a built-up area of 100,000 square feet in 2 phases, B-Hub will compliment the extraordinary ecosystem at Genome Valley in Hyderabad," he said, in a series of tweets.

The facility is being developed by the Telangana State Industrial Infrastructure Corporation Ltd and Telangana Life Sciences, in an unique partnership model with the Centre's Department of Biotechnology, Cytiva, and Cerestra Ventures.

"The project is envisioned to be an accelerator for biopharma innovation featuring next gen lab suites, encouraging both Startups & midsized companies to interact and collaborate through collective spaces and lead innovation," said Rama Rao.

According to an official note released from the minister's office, annual sales of biopharmaceuticals are now over $200 billion globally, and industry revenue continues to grow at 15 per cent annually. An increasing number and percentage of pharmaceuticals entering the market are biopharmaceuticals, with about 40 per cent of Big Pharma and overall pharmaceutical R&D/pipelines now involving biopharmaceuticals, not drugs (chemical substances).

A biopharma scale-up manufacturing facility with a turnkey laboratory space is a key requirement to facilitate the growth of biosimilars in the lifesciences industry. Biopharmaceutical companies are aspiring to advance a molecule from the laboratory to the clinic as quickly as possible without sacrificing product quality, process efficiency, or patient safety. To achieve this goal, companies must navigate the complexities associated with business planning, cell line development, process development, technology, and regulatory and risk assessment, it said.

There is no such full-fledged infrastructure anywhere in the country on date and establishment of an end-to-end biopharma upscale facility including bioreactors and vessels which contain cell culture media to the filtration units and the downstream chromatography processes will provide a platform for the start-ups, mid-sized and even large biopharma companies to carry out their pre-clinical validation in the proposed facility, before making significant capex investment in the product. (IANS)

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