New research published by Blood Advances shows that people with blood group 'O' are likely to have a lower risk of contracting the COVID-19 infection. The study conducted a retrospective cohort analysis of all Danish people of blood group ABO and RhD who tested for COVID-19 infection from February 27-July 30. The research led to analyze the influence of covid-19 on common blood groups.
The Coronavirus research study participants included 38% of the total Denmark population with 4,73,654 individuals who tested for COVID-19 using real-time polymerase chain reaction and 22,04,742 non-tested individuals. Out of these, 29% of the participants were male. The study also collected related information like hospitalization and death from the virus, cardiovascular health, and job statuses.
The development of viral infection is associated with a person's age, sex, and co-morbidities like cardiovascular diseases. Reports of ABO blood group showed that it might have a crucial part in the Coronavirus infection, with a low chance of contracting the virus. The blood group A and B affect glycosylation in different cells, including epithelial cells in persons' respiratory tracts. The A, B, and AB individuals are also at high risk for thrombosis and cardiovascular diseases. These two co-morbidities are most prevalent among hospitalized Sars-Cov-2 patients.
The research study also saw a slight, though the statistically crucial difference in the blood group distribution between the Sars-Cov-2 individuals and the reference group. Among the COVID-19 individuals, a fewer O blood group individuals were found, and more of A, B, and AB individuals were noted.
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